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中药学院导师简介-柴兴云

来源: 作者: 发布时间:2022-06-16

  

  所属学科:中药化学、民族药学

  导师简介:柴兴云

  个人简介:

  博士,研究员,博士生导师,研究生院副院长,从事民族药药效物质研究,着重从整体模式阐明特色民族药物防治缺血性心脏病的药效物质,主持了国家自然科学基金、中央本级重大增减支项目、省级重点研究计划等项目,担任中国民族医药学会科研分会副会长兼常务副秘书长、中国民族医药学会药用资源分会副会长、江西中医药大学硕士生兼职导师、西藏甘露医药科技有限公司外聘医药专家、Chemistry & Biodiversity和《中国中药杂志》编委、巴基斯多所大学的博士论文评审专家,获得2021年教育部高等学校科学研究优秀成果奖一等奖,发表了140余篇学术论文,包括SCI论文80余篇。

  联系方式:010-6428 6350;chaixingyun@126.com

  研究方向:

  1. 民族药防治缺血性心脏病的药效物质研究

  2. 基于双心同治特色的藏成药系统评价和开发

  科研成果:

  1. Li J., Ge F., Chai X., et al. Zerumbone, a humulane sesquiterpene from Syringa pinnatifolia, attenuates cardiac fibrosis through inhibition of the TGF-β/Smads signaling pathway after MI in mice. Phytomedicine, 2022, 100, 154078 (110).
  2. Jiao S., Su G., Chai X., et al. Three pairs of enantiomeric sesquiterpenoids from Syringa pinnatifolia. J Org Chem, 2021, 86: 7263–7270.
  3. Zhao F., Bai R., Chai X., et al. Meconopsis horridulaHook. f. & Thomson extract and its alkaloid oleracein E exert cardioprotective effects against acute myocardial ischaemic injury in mice. J Ethnopharmacol, 2020, 258: 112893 (1‒11).
  4. Feng X., Zhang R., Chai X., et al. Syringa pinnatifolia Hemsl. fraction protects against myocardial ischemic injury by targeting the p53-mediated apoptosis pathway. Phytomedicine, 2019, 52: 136‒146.
  5. Zhang R., Feng X., Chai X., et al. Bioactive sesquiterpenoids from the peeled stems of Syringa pinnatifolia. J Nat Prod, 2018, 81 (8): 1711–1720.
  6. Yang X., Gao X., Chai X., et al. The Ilex asprella aqueous extracts exert in vivo anti-inflammatory potential by regulating NF-κB, JAK2/STAT3, and MAPK signaling pathways. J Ethnopharmacol, 2018, 225: 234‒243.
  7. Bai R., Yin X., Chai X., et al. Corydalis hendersonii Hemsl. protects against myocardial injury by attenuating inflammation and fibrosis via NF-κB and JAK2-STAT3 signaling pathways. J Ethnopharmacol, 2017, 207: 174‒183.
  8. Yu X., Guo Q., Chai X., et al. Usnic acid derivatives with cytotoxic and antifungal activities from the lichen Usnea longissima, J Nat Prod, 2016, 79 (5): 1373–1380.
  9. Cao Y., Wang J., Chai X., et al. Anti-myocardial ischemia effect of Syringa pinnatifolia Hemsl. by inhibiting expression of cyclooxygenase-1 and -2 in myocardial tissues of mice. J Ethnopharmacol, 2016, 187: 259–268.
  10. 柴兴云. 试论中药涌现性特征. 中国中药杂志, 2015, 40 (13): 2480–2485.